The people said they were being held against their will.
Police are investigating a possible human smuggling operation after at least 26 people were found locked inside a home in southwest Houston.
Most of the people told police they were being held against their will and had been locked in the house from a few days to a week.
Investigators said the victims were picked up in Brownsville, Texas, but originally came from other countries, such as Mexico, Honduras, El Salvador and Cuba, KTRK reported.
The 26 people have since been taken to the Ridgemont Elementary School gym for shelter, police said.
Investigators are treating the case as a human smuggling operation and are cooperating with the United States Department of Homeland Security, police said on Twitter.
Houston police said they have possible suspects detained and are waiting on immigration officials to begin their investigation, KTRK reported.